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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3226428ec3cfb8bf7c52461789ae7aae7cf9350cf8771cdb2de90efd047d5981' 
  AND token = 'y8EpGj2hShVKTcKHz/lqlVrpSYAIlhDOHy3v9TkL4dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}