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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b00d9cdab4f1dc55d11f9f006e7b633a472c4c40d4454de510be1b2392ef82' 
  AND token = 'b2tMdHeB2w6jl2A6gR0k8LlM3LhF8pzZwc7yHUyC69s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}