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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c2601a84f55020395d4d81b36c5bc3b8f450482bae291e60687cc06d5964a47' 
  AND token = 't1iEeTPTL3o2sSmII/TI2S6sgfz3FtO4pj7FMwtAfXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}