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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54827a3fe0f81a42cdae59038b66a48ce41138b986fc0a0ea17b3e913cb45f03' 
  AND token = 'Scil5SdGlDJpdCVg9YOPqRxRqyRdhx9K33GtSv9AqZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}