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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '378df980e78a40de0dcee1a0dd1a60aa8c0f12d27d84284bff9360d1e6d7ba18' 
  AND token = 'te8Wg1QuU20jlBBY06y6F4tHBMQm8ISTvrauXh9uZzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}