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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8d00bc4b5d86e66262ddeaa5910f0026785faca6532b0dfc65430884f7e34b1' 
  AND token = 'lL1OYfI6UJqUQVt9uTfg5bsXZS0vsCqKCZjVSqeP8g0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}