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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee74a34226089700283c71158f9e91b9e9a4c4bcaa2425578d68a1a3f1adeb0c' 
  AND token = '6oF8wsmbc/BWFEuCL+Wc9VRmlssDRPIdm9LRnX8f8s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}