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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666be82f2e292f0d8a2d28d310845edca53cd759f21862c61fd87f37431d4879' 
  AND token = 'xNF6Tafqd8UhfzlemuyviKqk8WFYa+VGlt9nSCkUCOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}