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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2db839d19c0a5893c0e7be1a059669e3e399e4e4f56bd06a1364050849c10b29' 
  AND token = 'epsbuqA0E0RUyMyh0i0k9kLwsog+oYny/IYy99Y6kT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}