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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e66f4ed1fe48d2f526c72718a56c8649e03f827afd5bddf25d24ecf48d2c5d' 
  AND token = 'PGZlTOLrmBLVwoJP+jvZBib4g2xTZ4oAsWmP074Du1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00080

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}