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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2efb58ddf51d237a150dbb6f4b566dd37420288c7b04b4eede265a08f4618b3' 
  AND token = 'sT5dC3OHO01GCGyoTeCjoE7Bq/hdD6OJxqJvgZj7vEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}