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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67282b50c3163763d93788999eb7c398346f7a9c75a90b1ab28c56d117be7fc9' 
  AND token = 'TtnOxrV+SH8g27ud8t9i7iPTrdUcfcnIew6/c0uwmZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}