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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8838c8d7e981f654fd31fc6ba424b2dccade61b6dbd37bfde818e5447753258' 
  AND token = 'G/2CnXMHMk1V2/ZPcGzoXcVqtlGpe/DApfHW1ZzM9gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}