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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49bf897b2e7d7203cc37c7478211f80d79fa115f7d60bf7c2207be6b02e98905' 
  AND token = 's9W8kHOnTjW+BvAbiHDpsl5de0l8uNoTOHJarz9OI8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}