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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049db6b4e8d3d641f5c288bd3b94bf7a8601f7fc442505c84a981ee62e78b0a2' 
  AND token = 'qTeAYgcAiSBjkA/+r9wO14PkF0CxkJ03r2JFlXJpxz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}