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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e53f3bd491e69a1bccd2ce3decd49ac9eda677c7cc4b5dc370a044401402202' 
  AND token = '2VWWWDpWHEvuDnO4eW/Ikuk1YL/oai1SVbjxaLMf054=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}