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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ec96516736609bb599a88d86ec5a86f12e676c1de92775b899e4d8af285c54' 
  AND token = 'LvN9zDxraNTIzFT+49NKCZF2hQ/in8Oj9TQcSZ0+uko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}