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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '101d8c850c9f1d4c4f9e007bf8f39bc8b7380cde1d593683641e6c3cb3bb8a88' 
  AND token = 'S+sTIxBbKn1+Tok4VGy1ABXCc0gh42UAbJVX/g/uBIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}