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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1ecd69c9fc70cce059acfb64b28a0b200b49b701f5394d77f93fb59adffb3ee' 
  AND token = 'zFqWjSAN/SdjOcXBsd1bPHVG5dFRNoaanSxBb+l9WdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}