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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56a8dbb6bd0aacbfaf633e5f14d7637c7f5254cc349a943b99fa3d3a01774b73' 
  AND token = 'yRE4v76+9SOo03a2buPAH9PDtRVZ4pF+DffOy2K/ZUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}