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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f4022c4f64fd82f2441c89791075fd4e7db36d6de7295772bade21f04266ec' 
  AND token = 'au781HfwQWi2x5Ep43Rg0ETCQ7+9h3gjJn1pMn8iGsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}