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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52debf03b79a5c23f27256ac29d593715b4e99b5afcc08a3833358d99127bf19' 
  AND token = 'QB/NyUq8/4Y6nBtRTyRCmxZxffy74trSz6O63uP9ri4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}