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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '014d1c9eeb82b10dab45338fbde7de88dfe1dd60f077a68d114860d3611c3b9d' 
  AND token = 'xo5Sx55EDhz/YrKQqIDl9J+4S6X0UpN/Le4AapYv6Nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}