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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c05cb78f19cd4da163ccc92e428701614d50bbaa089e06187586bf0a8098c67' 
  AND token = 'madffS78N48U9y+1FktAl8SI3AvhKNb9q9+2HOBkyCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}