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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0181c2d825c5a409030f54b46c637a18da3001fda0768a1d40c8d31cdf94445' 
  AND token = 'gwXLFoLEBYcJiHgkpVkjzu1AX1tDw3AGA7G1EaXbscQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}