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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4357d730665a6f4d6b0e202c4081e9995daf670e10add1c6e4d7d16641f8ba6e' 
  AND token = 'BSCC7fVNLUAZAWj02TNj/kcFj5jlZt+q0ATH8jUjAN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}