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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4152564bb7ee9e9f0fc52b08e3d4f0ccf756ee00a5428f55059ce3fca29d4aae' 
  AND token = 'KO0TGNLw8dQzg2+Fi1/bp+EWG4TWrrK0vnkxKFXtbY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}