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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5e4bca32b1900ac9480a05061d49405f6131860f9898b3e5c042b9fc00138b7' 
  AND token = '3YM8RWa4kYlTp0hmmUe5scrfN+7c8yGtIecc79QWMG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}