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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '273e8fc9eaedc70f967b6f3e75fb4d52d30e370f536d6a77c5a2c78afb462b53' 
  AND token = 'iCXAxE6yTjQPGhcTcMKQn8QV5pa7oXKRwMnXfz+DT5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}