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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d84daf5725a1b5fe7629316bb739d73513b34b0fe7577662e93c2b2234ff0e1' 
  AND token = 'CvvmJJz/2dKtm92inv3VBLhFhN36uBL3KbtVzt/rOfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}