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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a9bafe1597b07f0c37f81f8e2391ed52a81e842d8d643230cdbd745180058e' 
  AND token = 'R/6NQQOWNZctTQr27vPctNrtLRy3F7T7Q1oFe/XjiAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}