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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de3c2e7c850c368c908befd40dbf4837575cbdd8dddd1f78227b2636021173ba' 
  AND token = 'ZdItl/Uud+dOZBnSVMiOoclpm0yLfakGlHv+EeyoVCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}