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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c68c3fa73f065bc9802671967feb00a2a7d646eae50ea20365e385b02a75666' 
  AND token = '/FrOcxlt6wlOtUGmsbnQNcnRm6rCYEwFRtUBPV3/qXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}