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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291a3f88dc8a21c8d521041f1ed7380d53f30c356fffe5a88296486e84b0fb72' 
  AND token = '3LFi+9vXt7ch1h2dA49cOW5Ciyjqe/zSNN5fxus9zlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}