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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed1cffe6107e64116f69d171fe32a1b1e58223dabb335ea4a8887ae9cb3ee0bb' 
  AND token = 'GZEyTiytZZ+4njjI/TqJWj41gCgIx+tDlBFDtqIlQYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}