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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb0c72e73b2106c3a95c34703827011c1716efc70f91083ad61bcf589c3d321' 
  AND token = 'jBWTm365Peo8smz/BNUYt/4RWxc1ToeKZeqmAisYQik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}