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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581478d2aa4b8e587880261c5766c25d5903fb2a02f5bf812c03c3898e3da600' 
  AND token = 'E3Xgxo9beS1eAsrwu78vV763eZ0izaFxTTxuFaNmKYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}