SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ea87e260abf3e7bb2971a318891a34e862b841dbebba21d28734aae1bd50b1e' 
  AND token = 'o+JZidb71u3dYAPv+h7PiztoFxpLPUrdKDal/+UgVQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}