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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea072655226e8567f13a6c30853c0d6796088b88017d7eee21e3d71bff7562f' 
  AND token = 'DOC1cZOX2IfqerGtGvhl5V6zc+u0rnjOz0b9zohoy5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}