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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ed91c8408402b6591ff6f461c21b50e1f91b32aef146e9fdaf7104d0125ee19' 
  AND token = 'UqA/rGhce71diFAq+g8W2gIG9tn2/4MXmqZvA2nlYKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}