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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f14d5e5cc779d6ea430c685bee3a5b7b754017244d5dd40d54afa3741d887d00' 
  AND token = 'OWOxGVcd9xuf2qbLQ0UFRWpwaBQcaS7E4gwBw1NdaXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}