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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6720161a653c0c8ef8a0aa7ed64b10f93df63cfbd29b0d9d1198089c8e14ad79' 
  AND token = 'GVi0EjLGBWLEjaIIkofzYmfaLDBGQeaKRp0IWWhmnBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}