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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c21d161b1df8ba4f93aa43bdeab8c54b6f95123ee51c0cd1c758a2d1c3d6f8f' 
  AND token = '+/RGpTbX3Qq6dHe/rvOHHYjX2FtTW3jjDPRievYrpiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}