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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f87f0dd6432c9bd966c30df992461253ad496a3ce3690c4effa8b0c2d4d0726' 
  AND token = 'AIKtMwWCiARKd/ZtgS7RCTbmxhDTSA4uIXfR+3Hd13A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}