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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ee2c4a637a02b76a49cd350da052adbfd303c74dc593744c3bdb91328c0a9a' 
  AND token = 'GZoGDskQbNJ6Swm+9cB4l98o6kftazJHIhyyAyXNYRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}