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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b885e16e3e5f1000f535ce86b626078eba106442f792093e2144f5ba6b854722' 
  AND token = 'EfGcyk/sgt7Zk6vOBtU3Wlq1xeeg6wex/vb+zQKvSf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}