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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40a04d97f1b527adc29aa4c843971f12d0c5eacbeb67024c91d4bf622a1f7f75' 
  AND token = 'E6KJ4vpH387u9Vu2Gko3tCAnyJNKJPbw+MHBUKnIlB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}