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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3554fc0b5d05215d3233e3256dde70ce45ec3ba4f5c57f2245b8883c25360ff6' 
  AND token = '+7uRNZNU9qXrcoN8bRHcRv+Wzo4l/BsnczkjJgMGfiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}