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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '253090ebcd7eed2838d47c2cb46d75dbf03e16d5feb8b5a9024322b8f7ad0b09' 
  AND token = 'bdB8oMkPy0EJ9rHOAHNgtmcyJi0CHqLj9Cdg50jnTMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}