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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '108301df049805ea1a593124820227a100583d9614717a652319378a95f93223' 
  AND token = 'XXOxiAaBBh8h2bf2TVkmZl1aPaDB70+fZmfrQ7Fm6r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}